1F20.01/B44.8 Invasive cerebral aspergillosis



Invasive cerebral aspergillosis is an infection caused by the fungus Aspergillus. It is most commonly seen in individuals with weakened immune systems, such as those with HIV/AIDS, those receiving chemotherapy, organ transplant recipients, and people with autoimmune diseases.


Diagnosis of invasive cerebral aspergillosis is typically made through a CT scan or MRI of the brain, as well as blood tests, urine tests, and cerebrospinal fluid tests.

Differential diagnosis

Differential diagnosis for invasive cerebral aspergillosis includes other fungal infections, such as cryptococcosis and meningitis, as well as bacterial and viral infections.


Treatment for invasive cerebral aspergillosis typically involves the use of antifungal medications, such as amphotericin B and fluconazole. Surgery may also be necessary in some cases.


The prognosis for individuals with invasive cerebral aspergillosis is typically poor, as the infection can be difficult to treat and can cause significant neurological damage. However, with early diagnosis and proper treatment, the prognosis can be improved.

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