Primary malignant meningioma is a rare and aggressive type of brain tumor that originates in the meninges, the protective membranes that surround the brain and spinal cord. The exact cause of primary malignant meningiomas is unknown, however, genetic mutations have been linked to the development of this type of tumor.
Diagnosis of primary malignant meningioma is made based on the patient’s symptoms, physical examination and medical imaging such as computed tomography (CT) or magnetic resonance imaging (MRI). A biopsy of the tumor may also be performed to confirm diagnosis.
Differential diagnosis for primary malignant meningiomas may include other types of brain tumors such as glioblastoma, ependymoma, and astrocytoma. Other conditions such as stroke, brain abscess, and hydrocephalus may also be considered.
Treatment options for primary malignant meningioma include surgery, radiation therapy, and chemotherapy. Surgery is the primary treatment for this type of tumor and may involve complete removal, partial removal, or a combination of both. Radiation therapy may also be used to shrink the tumor and reduce symptoms. Chemotherapy may be used to target the tumor cells and reduce the risk of recurrence.
The prognosis for primary malignant meningioma depends on the size and location of the tumor and the patient’s age and overall health. Generally, the prognosis is good if the tumor can be completely removed. However, recurrence is possible and may require further treatment.