2B54.Z/C41.9 Unclassified pleomorphic sarcoma, primary site, unspecified site



The exact cause of Unclassified Pleomorphic Sarcoma (UPS) is unknown. It is thought to be a result of either genetic mutations or environmental exposures.


UPS can be diagnosed through imaging tests such as X-rays, CT scans, and/or MRI scans. Tissue biopsies and laboratory tests may also be used to confirm the diagnosis.

Differential diagnosis

Differential diagnoses for UPS include other sarcomas, such as malignant fibrous histiocytoma, leiomyosarcoma, and liposarcoma.


Treatment of UPS typically involves surgery and/or chemotherapy. Radiation therapy may also be used. Surgery is often used to remove the tumor and any affected lymph nodes. Chemotherapy and radiation therapy are used to kill any remaining cancer cells.


The prognosis for UPS depends on the size and location of the tumor, as well as the patient’s overall health. In general, the prognosis is good if the tumor is removed completely and no cancer cells remain. However, if the tumor is not removed completely or if cancer cells remain, the prognosis may be poorer.

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