2B58.0/C41.9 Leiomyosarcoma of retroperitoneum or peritoneum



The exact cause of leiomyosarcoma of the retroperitoneum or peritoneum is unknown. However, it is thought to be associated with certain genetic mutations and some environmental factors, such as radiation exposure.


Leiomyosarcoma of the retroperitoneum or peritoneum can be diagnosed through imaging tests (CT scan and MRI) and biopsy.

Differential diagnosis

Other tumors that may need to be considered in the differential diagnosis include other sarcomas, such as leiomyoma and leiomyoblastoma, as well as other malignant tumors, such as lymphoma and carcinoma.


Treatment for leiomyosarcoma of the retroperitoneum or peritoneum typically includes surgery, chemotherapy, and radiation therapy. The extent of the treatment will depend on the size, location, and characteristics of the tumor.


The prognosis for leiomyosarcoma of the retroperitoneum or peritoneum is generally poor. The average 5-year survival rate is approximately 25-30%.

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