The cause of gastrointestinal stromal tumor (GIST) is not well understood. It is believed to be the result of a genetic mutation of the KIT or PDGFRA genes, which are responsible for controlling cell growth.
GIST is typically diagnosed through imaging tests such as CT scan or MRI, as well as endoscopic biopsy.
Differential diagnosis of GIST includes other types of tumors such as leiomyomas, schwannomas, adenocarcinomas, and inflammatory fibroid polyps.
Treatment of GIST depends on the size and location of the tumor, as well as the patient’s overall health. Surgery is often the first line of treatment, followed by chemotherapy or radiation therapy. Targeted therapies such as imatinib may also be used.
The prognosis for GIST depends on the size and location of the tumor, as well as the patient’s overall health. Early detection and treatment usually leads to a better prognosis.