2C21.1/C30.1 Squamous cell carcinoma of middle ear



Squamous cell carcinoma of the middle ear is a rare malignant tumor of the middle ear. It typically affects adults over the age of 50 and is more common in men than in women. It can be caused by chronic inflammation, chronic irritation, and genetic predisposition.


The diagnosis of squamous cell carcinoma of the middle ear is made based on a combination of clinical examination, imaging studies, and biopsy of the affected area. Clinical signs may include pain, hearing loss, tinnitus, a feeling of fullness in the ear, and/or a visible mass. Imaging studies such as CT scans or MRI may be used to identify the extent of the tumor. A biopsy of the affected area is then performed to confirm the diagnosis.

Differential diagnosis

The differential diagnosis for squamous cell carcinoma of the middle ear includes other malignant tumors such as adenocarcinoma, chondrosarcoma, and lymphoma. Benign tumors such as cholesteatoma and polyps may also present with similar signs and symptoms.


Treatment for squamous cell carcinoma of the middle ear usually consists of surgical removal of the tumor. It may be necessary to remove the entire middle ear, depending on the size and location of the tumor. Radiation therapy and/or chemotherapy may also be used, depending on the extent of the tumor.


The prognosis for squamous cell carcinoma of the middle ear depends on the size and extent of the tumor. Early diagnosis and treatment increases the chances of a successful outcome.

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