Aetiology
Other specified acquired aplastic anaemias (OSAAA) is a rare type of aplastic anaemia caused by an underlying condition such as exposure to toxins, medications, infections, radiation, autoimmune disorders, or a genetic predisposition.
Diagnosis
Diagnosis of OSAAA is based on a complete medical history including exposure to toxins, medications, infections, and radiation, along with laboratory tests including complete blood count, reticulocyte count, and peripheral blood smear.
Differential diagnosis
Differential diagnosis includes other types of aplastic anaemia, such as Fanconi anaemia, myelodysplastic syndrome, and paroxysmal nocturnal haemoglobinuria.
Treatment
Treatment of OSAAA depends on the underlying cause and may include removal of the causative agent, supportive care (transfusions, antibiotics, and growth factors), immunosuppressive therapy, and bone marrow transplantation.
Prognosis
Prognosis depends on the underlying cause and the severity of the anaemia, but in general, the prognosis is poor.