3B61.Y/D68.8 Other specified thrombophilia



Other specified thrombophilia is a group of inherited blood disorders that cause abnormal blood clotting. It is caused by mutations in genes that control the body’s coagulation system, leading to a hypercoagulable state. Risk factors for Other specified thrombophilia include a family history of blood clots, a personal history of blood clots, and certain lifestyle choices such as smoking, being overweight, and being sedentary.


Diagnosis of Other specified thrombophilia is based on a history and physical examination, laboratory testing, and imaging studies. Blood tests such as the prothrombin time (PT), activated partial thromboplastin time (aPTT), and D-dimer can help confirm the diagnosis. Genetic testing can also be used to identify specific gene mutations that are associated with Other specified thrombophilia.

Differential diagnosis

Other specified thrombophilia should be differentiated from other conditions that can cause abnormal blood clotting, such as deep vein thrombosis, pulmonary embolism, Factor V Leiden, and antiphospholipid syndrome.


Treatment of Other specified thrombophilia is aimed at reducing the risk of recurrent blood clots. This may include lifestyle modifications such as avoiding smoking and maintaining a healthy weight. Medications such as anticoagulants may also be prescribed to reduce the risk of blood clots.


The prognosis for Other specified thrombophilia is generally good with proper treatment and lifestyle modifications. However, the risk of recurrent blood clots remains even with treatment, so it is important to be aware of the signs and symptoms of a blood clot and to seek medical attention promptly if they occur.

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