Aetiology
Other specified coagulation defects, purpura or other haemorrhagic or related conditions, can be caused by a number of different factors, including inherited genetic disorders, certain medications, infections, autoimmune disease, liver disease and vitamin K deficiency.
Diagnosis
The diagnosis of this condition can be made through a variety of tests, such as a complete blood count, coagulation tests, platelet count, prothrombin time, activated partial thromboplastin time, and factor assays.
Differential diagnosis
Differential diagnosis should include conditions such as thrombocytopenia, thrombotic thrombocytopenic purpura, von Willebrand disease, hemophilia, and other conditions affecting the coagulation cascade.
Treatment
Treatment of this condition will vary depending on the underlying cause. If a genetic disorder is responsible for the condition, then gene therapy may be an option. If a medication is the cause, then switching or stopping the offending medication may be necessary. Other treatments may include vitamin K supplementation, transfusion of fresh frozen plasma, or immunosuppressive therapy.
Prognosis
The prognosis of this condition will depend on the underlying cause and the severity of the condition. If the condition is caused by a genetic disorder, then the prognosis may be poor. However, if the condition is caused by a medication, then the prognosis may be more favorable.