4A44.3/M30-M36 Single organ vasculitis



Single organ vasculitis is an inflammatory disorder that affects a single organ, such as the kidneys, lungs, heart, brain, or skin. It is caused by an abnormal immune system response that produces inflammation in the affected organ’s blood vessels. This inflammation can lead to thickening of the walls of the vessels, narrowing of the lumen, and occlusion of the vessel.


Diagnosis of single organ vasculitis is made through a combination of physical examination, laboratory tests, imaging studies, and biopsy. Blood tests such as erythrocyte sedimentation rate and C-reactive protein can be used to detect inflammation. Imaging studies such as CT scans and MRI can help to identify any narrowing of blood vessels or plaque buildup. Biopsy of the affected organ can help to confirm the diagnosis and identify any specific type of vasculitis.

Differential diagnosis

Other conditions that can cause inflammation in the blood vessels such as atherosclerosis, thrombosis, or infection should also be considered in the differential diagnosis.


Treatment of single organ vasculitis depends on the type and severity of the condition. Corticosteroids and immunosuppressive drugs are often used to reduce inflammation and prevent further damage. Other treatments such as angioplasty may be necessary to open narrowed vessels.


The prognosis for single organ vasculitis depends on the type and severity of the condition. With proper treatment, most patients can expect to return to normal activities. However, some patients may experience long-term complications, such as organ damage or scarring.

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