Increased secretion of glucagon can occur due to various causes, including excessive consumption of alcohol and some medications, as well as liver and pancreatic diseases.
Diagnosis of increased glucagon levels can be done through a blood test.
Differential diagnosis should include other causes of hyperglycemia such as diabetes, Cushing’s syndrome, and pheochromocytoma.
Treatment will depend on the underlying cause of the increased glucagon levels. In some cases, lifestyle modifications, such as limiting alcohol consumption and maintaining a healthy diet, may help to reduce glucagon levels. Medications such as insulin and other diabetes medications may be prescribed to help regulate blood sugar levels.
The prognosis for increased glucagon levels varies depending on the underlying cause. In cases where lifestyle modifications have helped to reduce glucagon levels, the prognosis is generally good. In cases where underlying medical conditions are causing the elevated levels, the prognosis can vary.