5A61.4/E23 Thyroid stimulating hormone deficiency



Thyroid stimulating hormone deficiency is caused by a disorder of the pituitary gland, which is responsible for the production of TSH. It can also be caused by an autoimmune disorder, a genetic disorder, or a tumor in the pituitary gland.


Thyroid stimulating hormone deficiency is diagnosed through a blood test that measures the amount of TSH in the bloodstream. Other tests, such as an ultrasound or MRI of the pituitary gland, may also be ordered to confirm the diagnosis.

Differential diagnosis

Other conditions that may mimic the symptoms of TSH deficiency include hypothyroidism, hyperthyroidism, and pituitary adenomas.


Treatment for TSH deficiency usually involves hormone replacement therapy with synthetic TSH. This is done to restore normal thyroid hormone levels and treat any symptoms that may be present.


With proper treatment, the prognosis for TSH deficiency is generally good. Patients may need to take hormone replacement therapy for life in order to manage their condition.

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