Aetiology
Disorders of bilirubin metabolism or excretion can be caused by a variety of factors, including genetic mutations, infections, liver diseases, and certain medications.
Diagnosis
Diagnosis for disorders of bilirubin metabolism or excretion is typically done through blood tests, imaging tests, and biopsies. The blood test will measure the levels of bilirubin, enzymes, and other related substances in the blood. Imaging tests, such as CT scans or MRIs, may be used to look at the liver and other organs. A biopsy may be done to look at the structure of the liver.
Differential diagnosis
Differential diagnosis for disorders of bilirubin metabolism or excretion include other liver diseases, such as cirrhosis, hepatitis, and biliary atresia, as well as other metabolic disorders.
Treatment
Treatment for disorders of bilirubin metabolism or excretion depends on the underlying cause. Treatment may include medications, dietary changes, and lifestyle modifications. In some cases, surgery may be necessary.
Prognosis
The prognosis for disorders of bilirubin metabolism or excretion varies depending on the underlying cause. In some cases, the disorder may be managed with lifestyle and dietary changes, while in other cases, more aggressive treatments may be necessary.