6A21.01/F25 Schizoaffective disorder, first episode, in partial remission



Schizoaffective disorder is a psychiatric disorder characterized by symptoms of both schizophrenia and a mood disorder, such as depression or bipolar disorder. The exact cause of schizoaffective disorder is unknown, however, research suggests that a combination of genetic, environmental, and psychological factors may play a role.


Schizoaffective disorder is diagnosed based on the criteria outlined in the Diagnostic and Statistical Manual of Mental Disorders (DSM-5). In order to be diagnosed with schizoaffective disorder, a patient must have experienced at least two weeks of psychotic symptoms and a period of significant mood disturbance. In addition, the symptoms must not be better explained by another mental disorder or medical condition.

Differential diagnosis

Schizoaffective disorder must be differentiated from schizophrenia, bipolar disorder, and other mood disorders. Schizophrenia is diagnosed when a patient experiences at least two weeks of psychotic symptoms without a period of significant mood disturbance. Bipolar disorder is diagnosed when a patient experiences at least one episode of mania or hypomania in addition to depressive symptoms.


Treatment for schizoaffective disorder typically involves a combination of pharmacological and psychosocial interventions. Medications such as antipsychotics, mood stabilizers, and antidepressants are commonly used to stabilize symptoms and reduce the risk of relapse. In addition, psychosocial interventions such as cognitive-behavioral therapy, psychoeducation, and family therapy are often used to address the social, emotional, and behavioral aspects of the disorder.


The prognosis for schizoaffective disorder is generally favorable, especially when treatment is initiated early and symptoms are well-managed. However, it is important to note that relapse is common and that the severity of symptoms can vary over time. With ongoing treatment and support, individuals with schizoaffective disorder can often lead healthy, productive lives.

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