8A21.Z/G30-G32 Progressive focal atrophies, unspecified



The cause of progressive focal atrophies is unknown. It is thought to be related to genetic or metabolic abnormalities, or a combination of both.


Diagnosis of progressive focal atrophies requires a thorough clinical evaluation, including a detailed medical history, physical examination, and laboratory testing. Magnetic resonance imaging (MRI) and computed tomography (CT) scans may be used to identify the areas of atrophy.

Differential diagnosis

Differential diagnosis may include other neurological disorders such as multiple sclerosis, amyotrophic lateral sclerosis (ALS), or Huntington’s disease.


Treatment of progressive focal atrophies is supportive, focusing on relieving symptoms. Medications such as anti-inflammatory drugs or steroids may be used to reduce inflammation and improve mobility. Physical therapy may be recommended to maintain muscle strength and flexibility.


The prognosis for progressive focal atrophies is variable and dependent on the severity of the condition and the individual’s response to treatment. In some cases, the condition may be reversible, while in others it may progress slowly over time.

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