Acute haemorrhagic leukoencephalitis (AHLE) is a rare and severe autoimmune disorder that affects the white matter of the brain. It is believed to be caused by an immune reaction to an infection such as a virus, bacteria, or fungi.
Diagnosis of AHLE can be made based on clinical history and physical examination, as well as imaging studies such as MRI. MRI will show evidence of white matter abnormalities, including areas of increased signal intensity, which is an indication of inflammation.
Differential diagnosis of AHLE includes other diseases that can cause similar white matter abnormalities such as multiple sclerosis, encephalitis, and cerebral vasculitis.
Treatment of AHLE is primarily supportive, including immunosuppressive medications and corticosteroids.
Prognosis of AHLE is variable and depends on the severity of the disease, but most patients recover with treatment.