8C75/G71 Distal myopathies



Distal myopathies are a group of muscle disorders which result in weakness of the muscles in the hands, feet and lower legs. The cause of these myopathies is not known and they can occur at any age.


Diagnosis of distal myopathies is based on a physical examination and specific muscle strength testing. Other tests may be needed to rule out other conditions such as peripheral neuropathy, diabetes, myasthenia gravis or vasculitis.

Differential diagnosis

Differential diagnosis includes polymyositis, peripheral neuropathy, myasthenia gravis, vasculitis and other causes of muscle weakness.


Treatment for distal myopathies is aimed at managing symptoms and maintaining muscle strength and function. Treatment may include physical therapy, medications to reduce inflammation, and/or lifestyle modifications.


The prognosis for distal myopathies is generally good. Most people with distal myopathies can expect to regain some muscle strength and function with treatment. In some cases, however, the condition may be progressive, leading to muscle weakness and disability.

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