8D88.0/G99.1 Autonomic neuropathy due to sodium channelopathies

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Aetiology

Autonomic neuropathy due to sodium channelopathies is an uncommon inherited disorder caused by mutations in sodium channel genes, which lead to abnormal sodium channel function. These mutations can affect autonomic neurons, leading to dysfunction of the autonomic nervous system.

Diagnosis

Diagnosis of Autonomic neuropathy due to sodium channelopathies is based on a combination of clinical signs and symptoms, family history, and genetic testing. Symptoms may include orthostatic hypotension, postural tachycardia syndrome, gastrointestinal symptoms, and bladder dysfunction.

Differential diagnosis

The differential diagnosis for Autonomic neuropathy due to sodium channelopathies includes other causes of autonomic neuropathy such as diabetes, multiple system atrophy, and amyloidosis.

Treatment

Treatment for Autonomic neuropathy due to sodium channelopathies is focused on symptom management and can include medications to control blood pressure and heart rate, medications to treat gastrointestinal symptoms, and medications to treat bladder dysfunction.

Prognosis

The prognosis for Autonomic neuropathy due to sodium channelopathies is generally good with proper management, however, the symptoms may worsen over time.

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DISCLAIMER: Please note that all explAInations are generated by AI and are not fact checked by a medical professional. ICD ExplAIned do not assume liability for any injuries or harm based on the use of this medical information.