Multi organ failure (MOF) is a condition where multiple organs in the body are not functioning normally, leading to a wide range of symptoms and complications. It is usually caused by a severe illness or injury, such as sepsis, a serious infection, traumatic injury, or a major surgery. The condition can also be caused by chronic diseases such as diabetes, liver or kidney diseases, or cancer.
The diagnosis of MOF is based on a physical exam, lab tests, imaging studies, and other tests. The doctor will look for signs of organ dysfunction, such as abnormal heart rate, low blood pressure, and low oxygen levels in the blood. The doctor may also order tests to check for infections, electrolyte imbalances, or other potential causes.
The differential diagnosis for MOF includes other conditions that can cause similar symptoms. These include acute kidney injury, sepsis, shock, and other conditions that cause organ dysfunction.
Treatment for MOF depends on the underlying cause. The goal of treatment is to stop the progression of the disease and restore the normal functioning of the affected organs. Treatment may include medications to reduce inflammation, antibiotics to treat infections, and supportive care to provide nutrition and hydration.
The prognosis for MOF depends on the underlying cause and how quickly treatment is started. In general, the prognosis is better for those who receive early and appropriate treatment. If the condition is not treated promptly, it can be fatal.